日本語
NIHON UNIVERSITY's 
College of Bioresource Sciences 
Department of Applied Biological Science 

Updated : 2019/11/21 
Associate Professor 
ARAI Naoto 

 
My website is here.  

Career (Number of the published data : 7)
Riken Institute (The Institute of Physical and Chemical Research),  バイオデザイン研究グループ  Postdoctoral Associate  1992/04-1992/10 
Cornell University Medical College,  Department of Microbiology  Postdoctoral Associate  1992/11-1994/10 
Riken Institute (The Institute of Physical and Chemical Research)  バイオデザイン研究グループ/遺伝生化学研究室  Postdoctoral Associate  1994/11/01-1995/12/31 
Japan Science and Technology Corporation (JST),  国際共同研究神経遺伝子プロジェクト  Research Associate  1996/01/01-1997/03/31 
Nihon University College of Bioresource Sciences,  Department of Applied Biological Science,  Research Associate  1997/04/01-2000/03/31 
Nihon University College of Bioresource Sciences,  Department of Applied Biological Science  Assistant Professor  2000/04/01-2017/03/31 
Nihon University College of Bioresource Sciences,  Department of Applied Biological Science  Associate Professor  2017/04/01-Present 

Academic background (Number of the published data : 3)
Nihon University  Faculty of Agriculture and Veterinary Medicine  農芸化学科  1987  Graduated  Domestic 
Nihon University  Graduate School, Division of Agriculture  Agricultural Chemistry  Doctor prophase  1989/03/25  Completed  Domestic 
Saitama University  Graduate School, Division of Science and Engineering  Department of Biological and Environmental Sciences  Doctor later  1992/03/31  Completed  Domestic 

Current state of research and teaching activities
Biochemical study of proteins related to homologous recombination in budding yeast. 

Research Areas (Number of the published data : 2)
Biochemistry of Genes 
Molecular biology 

Research keywords (Number of the published data : 5)
遺伝子 
homologous recombination 
yeast 
DNA 
DNA double strand break and repair 

Subject of research (Number of the published data : 2)
Study on Homologous recombination of Eucaryotes  1986-Present 
出芽酵母Rad51, Rad52の生化学、遺伝学、分子生物学的研究  1997/04-Present 
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Proposed theme of joint or funded research (Number of the published data : 1)
遺伝的組換えの解析、利用 
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Achievements of joint or funded research (Number of the published data : 2)
相同DNA組換え開始自在制御による新規ゲノム多様化機構の検証と標的組換えの実現  2014-2014 
新学術領域研究「天然変性タンパク質の分子認識機構と機能発現」研究領域計画研究 組換え酵素における天然変性領域の機能  2012-2013 
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Bibliography (Number of the published data : 3)
酵母からのDNA結合タンパク質(RPA)の精製方法  「タンパク質実験マニュアル」,朝倉書店  2006/10/25 
出芽酵母のDNA組換えタンパク質Rad52の精製法  「タンパク質実験マニュアル」,朝倉書店  2006/10/25 
出芽酵母のDNA組換えタンパク質Rad51の精製法  「タンパク質実験マニュアル」,朝倉書店  2006/10/25 
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Papers (Number of the published data : 14)
Nonfilament-forming RecA dimer catalyzes homologous joint formation  Nucleic Acids Research  2018/10/04  10.1093/nar/gky877 
Rad51 and RecA juxtapose dsDNA ends ready for DNA ligase-catalyzed end-joining under recombinase-suppressive conditions  Nucleic acids Research  2017/01/09  10.1093/nar/gkw998 
Loop L1 governs the DNA-binding specificity and order for RecA catalyzed reactions in homologous recombination and DNA repair  Nucleic Acids Research  2015/01/05  10.1093/nar/gku1364 
Functional analyses of the C terminal half of the Saccharomyces cerevisiae Rad52 protein  Nucleic Acids Reseach  2014/01 
Vital roles of the second DNA binding site of Rad52 in yeast homologous recombination  The Journal of Biological Chemistry  2011/05/20 
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Research presentations (Number of the published data : 72)
Oral presentation(general)  Roles of 2’ CH2 of deoxyribose in homologous recombination: Why do chromosomes consist of DNA?  第37回染色体ワークショップ・第18回核ダイナミクス研究会  2019/12/22 
Poster presentation  Requirement of DNA-binding sites of Rad52 for stimulation of DNA ends-joining catalyzed by DNA ligase.  第42回日本分子生物学会年会  2019/12/04 
Poster presentation  Rad51重合体形成の欠損変異の解析  第41回日本分子生物学会年会  2018/11/30 
Poster presentation  Rad52による DNA分子間の末端結合の促進  第41回日本分子生物学会年会  2018/11/30 
Poster presentation  出芽酵母 Rad52の C末端 DNA結合領域の機能  第41回日本分子生物学会年会  2018/11/30 
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Intellectual property rights (Number of the published data : 1)
Patent  RecA組換え酵素および組換え活性をもつ蛋白質を用いた直鎖二重鎖DNA多量体形成技術 
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Alloted class (Number of the published data : 8)
核酸・蛋白質概論 
応用生物科学実験IV 
分子生物学 
代謝生物学 
応用生物科学実験I 
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Memberships of academic societies (Number of the published data : 4)
日本分子生物学会 
日本生化学会 
American Society for Biochemistry and Molecular Biology (ASBMB) 
Federation of American Societies for Experimental Biology (FASEB) 
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